sage decreases results of diazepam by pharmacodynamic antagonism. Small/Significance Unknown. Theoretical conversation; some species of sage may well trigger convulsions.
nevirapine will minimize the level or outcome of diazepam by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch.
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Keep away from or substitute A different drug for these medicines when achievable. Assess for loss of therapeutic influence if medication need to be coadministered.
Reserve concomitant prescribing of such drugs in clients for whom other remedy selections are insufficient. Restrict dosages and durations into the minimum amount required. Check intently for signs of respiratory melancholy and sedation.
deferasirox will lessen the extent or outcome of diazepam by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch.
Coadministration of encorafenib with sensitive CYP3A4 substrates might bring about greater toxicity or diminished efficacy of these brokers.
fentanyl transdermal and diazepam the two enhance sedation. Steer clear of or Use Alternate Drug. Restrict use to people for whom choice cure choices are inadequate
topiramate will lessen the level or impact of diazepam by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check.
Coadministration of other CNS depressants or alcohol use may possibly potentiate CNS-depressant effects of diazepam
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sage decreases outcomes of diazepam by pharmacodynamic antagonism. Minimal/Importance Not known. Theoretical conversation; some species of sage might trigger convulsions.
Inappropriate or excessive utilization of diazepam can lead to dependence. At a very significant chance for diazepam misuse, substance use disorder or dependence are:
In here many, but not these scenarios, buprenorphine was misused by self-injection. If a benzodiazepine have to be useful for an indication other than seizures, lower the benzodiazepine First dose and cautiously titrate to scientific response.Serious - Use Different (one)buprenorphine subdermal implant and diazepam each increase sedation. Prevent or Use Alternate Drug. Limit use to clients for whom substitute remedy alternatives are insufficient